The Thermacell C-4 fuel pack effectively repels mosquitoes for up to 48 hours by creating a protection zone of 4.5 meters when used with Thermacell devices and repellent mats. Use this fuel refill only when you have spare Thermacell repellent mats. The heat produced by a Thermacell fuel cartridge is directed towards a small mat infused with Allethrin repellent, a synthetic version of a natural repellent found in chrysanthemum flowers. For optimal results, use on days with little or no wind (when insects are most active) and allow 10 to 15 minutes for a complete protection zone to form around the device.